Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity

Apolipoprotein (APOE) e4 genotype is an accepted risk factor for accelerated cognitive aging and dementia, though its neurostructural substrates are unclear. The deleterious effects of this genotype on brain structure may increase in magnitude into older age. This study aimed to investigate in UK Bi...

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Gepubliceerd in:Brain Imaging Behav
Hoofdauteurs: Lyall, Donald M., Cox, Simon R., Lyall, Laura M., Celis-Morales, Carlos, Cullen, Breda, Mackay, Daniel F., Ward, Joey, Strawbridge, Rona J., McIntosh, Andrew M., Sattar, Naveed, Smith, Daniel J., Cavanagh, Jonathan, Deary, Ian J., Pell, Jill P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2019
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572345/
https://ncbi.nlm.nih.gov/pubmed/30903549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11682-019-00069-9
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