EBV‐LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer

An Epstein‐Barr virus (EBV)—encoded latent membrane protein 1 (LMP1) is a principal oncogene that plays a pivotal role in EBV‐associated malignant tumors including nasopharyngeal cancer (NPC). Recent genomic landscape studies revealed that NPC also contained many genomic mutations, suggesting the ro...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Wakae, Kousho, Kondo, Satoru, Pham, Hai Thanh, Wakisaka, Naohiro, Que, Lusheng, Li, Yingfang, Zheng, Xin, Fukano, Kento, Kitamura, Kouichi, Watashi, Koichi, Aizaki, Hideki, Ueno, Takayoshi, Moriyama‐Kita, Makiko, Ishikawa, Kazuya, Nakanishi, Yosuke, Endo, Kazuhira, Muramatsu, Masamichi, Yoshizaki, Tomokazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571841/
https://ncbi.nlm.nih.gov/pubmed/32815637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3357
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