Targeting 14-3-3ζ Overcomes Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Lung Adenocarcinoma via BMP2/Smad/ID1 Signaling

Background: The 14-3-3ζ protein, which acts as a putative oncoprotein, has been found to promote the proliferation, metastasis, and chemoresistance of cancer cells in several cancers including lung adenocarcinoma (LUAD); however, its significance in epidermal growth factor receptor–tyrosine kinase i...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Cui, Jinfang, Song, Yang, Han, Xuejiao, Hu, Jing, Chen, Yanbo, Chen, Xuesong, Xu, Xiaomin, Xing, Ying, Lu, Hailing, Cai, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571474/
https://ncbi.nlm.nih.gov/pubmed/33123465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.542007
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