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Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma

Somatic mutations that lead to hyperactivation of epidermal growth factor receptor (EGFR) signaling are detected in approximately 50% of lung adenocarcinoma in people from the Far East population and tyrosine kinase inhibitors are now the standard first line treatment for advanced disease. They have...

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Bibliografiska uppgifter
I publikationen:Tuberc Respir Dis (Seoul)
Huvudupphovsmän: Chang, Yoon Soo, Choi, Chang-Min, Lee, Jae Cheol
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Korean Academy of Tuberculosis and Respiratory Diseases 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077728/
https://ncbi.nlm.nih.gov/pubmed/27790276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2016.79.4.248
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