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Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma
Somatic mutations that lead to hyperactivation of epidermal growth factor receptor (EGFR) signaling are detected in approximately 50% of lung adenocarcinoma in people from the Far East population and tyrosine kinase inhibitors are now the standard first line treatment for advanced disease. They have...
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| 發表在: | Tuberc Respir Dis (Seoul) |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Korean Academy of Tuberculosis and Respiratory Diseases
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077728/ https://ncbi.nlm.nih.gov/pubmed/27790276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2016.79.4.248 |
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