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Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma

Somatic mutations that lead to hyperactivation of epidermal growth factor receptor (EGFR) signaling are detected in approximately 50% of lung adenocarcinoma in people from the Far East population and tyrosine kinase inhibitors are now the standard first line treatment for advanced disease. They have...

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書目詳細資料
發表在:Tuberc Respir Dis (Seoul)
Main Authors: Chang, Yoon Soo, Choi, Chang-Min, Lee, Jae Cheol
格式: Artigo
語言:Inglês
出版: The Korean Academy of Tuberculosis and Respiratory Diseases 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077728/
https://ncbi.nlm.nih.gov/pubmed/27790276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2016.79.4.248
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