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Strategies for Overcoming Resistance to EGFR Family Tyrosine Kinase Inhibitors

The first-generation epidermal growth factor receptor tyrosine kinase inhibitors erlotinib and gefitinib have been incorporated into treatment paradigms for patients with advanced non-small cell lung cancer. These agents are particularly effective in a subset of patients whose tumors harbor activati...

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Detalhes bibliográficos
Main Authors: Giaccone, Giuseppe, Wang, Yisong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139833/
https://ncbi.nlm.nih.gov/pubmed/21367530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2011.01.003
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