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Id2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF-β-independent melanoma

The role for the inhibitors of differentiation (Ids) proteins in melanomagenesis has been poorly explored. In other cell types, Ids have been shown to contribute to cell proliferation, migration and angiogenesis and, along with a number of other genes, are direct downstream targets of the transformi...

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Библиографические подробности
Главные авторы: DiVito, Kyle A., Simbulan-Rosenthal, Cynthia M., Chen, You-Shin, Trabosh, Valerie A., Rosenthal, Dean S.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031572/
https://ncbi.nlm.nih.gov/pubmed/24343358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt479
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