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Id2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF-β-independent melanoma

The role for the inhibitors of differentiation (Ids) proteins in melanomagenesis has been poorly explored. In other cell types, Ids have been shown to contribute to cell proliferation, migration and angiogenesis and, along with a number of other genes, are direct downstream targets of the transformi...

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Bibliografske podrobnosti
Main Authors: DiVito, Kyle A., Simbulan-Rosenthal, Cynthia M., Chen, You-Shin, Trabosh, Valerie A., Rosenthal, Dean S.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031572/
https://ncbi.nlm.nih.gov/pubmed/24343358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt479
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