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Sequestration of E12/E47 and suppression of p27(KIP1) play a role in Id2-induced proliferation and tumorigenesis
Id2 is a member of the helix-loop-helix (HLH) family of transcription regulators known to antagonize basic HLH transcription factors and proteins of the retinoblastoma tumor suppressor family and is implicated in the regulation of proliferation, differentiation, apoptosis and carcinogenesis. To inve...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704286/ https://ncbi.nlm.nih.gov/pubmed/19451188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp115 |
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