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Sequestration of E12/E47 and suppression of p27(KIP1) play a role in Id2-induced proliferation and tumorigenesis

Id2 is a member of the helix-loop-helix (HLH) family of transcription regulators known to antagonize basic HLH transcription factors and proteins of the retinoblastoma tumor suppressor family and is implicated in the regulation of proliferation, differentiation, apoptosis and carcinogenesis. To inve...

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Hlavní autoři: Trabosh, Valerie A., Divito, Kyle A., D. Aguda, Baltazar, Simbulan-Rosenthal, Cynthia M., Rosenthal, Dean S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704286/
https://ncbi.nlm.nih.gov/pubmed/19451188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp115
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