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Molecular and Cellular Substrates for the Friedreich Ataxia. Significance of Contactin Expression and of Antioxidant Administration

In this study, the neural phenotype is explored in rodent models of the spinocerebellar disorder known as the Friedreich Ataxia (FA), which results from mutations within the gene encoding the Frataxin mitochondrial protein. For this, the M12 line, bearing a targeted mutation, which disrupts the Frat...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Bizzoca, Antonella, Caracciolo, Martina, Corsi, Patrizia, Magrone, Thea, Jirillo, Emilio, Gennarini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570916/
https://ncbi.nlm.nih.gov/pubmed/32906751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184085
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