Novel Bis-Ammonium Salts of Pyridoxine: Synthesis and Antimicrobial Properties

A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum inhibitory concentration (MIC) 0.25–16 µg/mL) comparable or s...

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Publicat a:Molecules
Autors principals: Shtyrlin, Nikita V., Pugachev, Mikhail V., Sapozhnikov, Sergey V., Garipov, Marsel R., Vafina, Rusalia M., Grishaev, Denis Y., Pavelyev, Roman S., Kazakova, Renata R., Agafonova, Mariya N., Iksanova, Alfiya G., Lisovskaya, Svetlana A., Zeldi, Marina I., Krylova, Elena S., Nikitina, Elena V., Sabirova, Alina E., Kayumov, Airat R., Shtyrlin, Yurii G.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570726/
https://ncbi.nlm.nih.gov/pubmed/32971844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184341
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