Novel Bis-Ammonium Salts of Pyridoxine: Synthesis and Antimicrobial Properties

A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum inhibitory concentration (MIC) 0.25–16 µg/mL) comparable or s...

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Pubblicato in:Molecules
Autori principali: Shtyrlin, Nikita V., Pugachev, Mikhail V., Sapozhnikov, Sergey V., Garipov, Marsel R., Vafina, Rusalia M., Grishaev, Denis Y., Pavelyev, Roman S., Kazakova, Renata R., Agafonova, Mariya N., Iksanova, Alfiya G., Lisovskaya, Svetlana A., Zeldi, Marina I., Krylova, Elena S., Nikitina, Elena V., Sabirova, Alina E., Kayumov, Airat R., Shtyrlin, Yurii G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570726/
https://ncbi.nlm.nih.gov/pubmed/32971844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184341
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