Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus

Glucokinase is one of the promising targets for glucose-lowering agents, and the development of GK activators are now considered as one of the most promising strategies for the treatment of type 2 diabetes mellitus. In this work, a series of novel symmetric molecular constructs, in which two pyridox...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dzyurkevich, Mikhail S., Babkov, Denis A., Shtyrlin, Nikita V., Mayka, Olga Yu., Iksanova, Alfiya G., Vassiliev, Pavel M., Balakin, Konstantin V., Spasov, Alexander A., Tarasov, Vadim V., Barreto, George, Shtyrlin, Yurii G., Aliev, Gjumrakch
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700121/
https://ncbi.nlm.nih.gov/pubmed/29167582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16405-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados