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Antisense Oligonucleotides Used to Identify Telomeric G-Quadruplexes in Metaphase Chromosomes and Fixed Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci

Identification of the existence of G-quadruplex (G4) structure, from a specific G-rich sequence in cells, is critical to the studies of structural biology and drug development. Accumulating evidence supports the existence of G4 structure in vivo. Particularly, time-gated fluorescence lifetime imagin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tseng, Ting-Yuan, Liu, Shin-Ya, Wang, Chiung-Lin, Chang, Ta-Chau
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570708/
https://ncbi.nlm.nih.gov/pubmed/32906697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184083
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