Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions

BACKGROUND: Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response. Emerging data reveal NK cell dysfunction within the tumor microenv...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Russick, Jules, Joubert, Pierre-Emmanuel, Gillard-Bocquet, Mélanie, Torset, Carine, Meylan, Maxime, Petitprez, Florent, Dragon-Durey, Marie-Agnes, Marmier, Solenne, Varthaman, Aditi, Josseaume, Nathalie, Germain, Claire, Goc, Jérémy, Dieu-Nosjean, Marie-Caroline, Validire, Pierre, Fournel, Ludovic, Zitvogel, Laurence, Bindea, Gabriela, Lupo, Audrey, Damotte, Diane, Alifano, Marco, Cremer, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Basic Tumor Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570244/
https://ncbi.nlm.nih.gov/pubmed/33067317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001054
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