Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

Compelling evidence suggests that inflammation, cell survival, and cancer are linked, with a central role played by NF-κB. Recent studies implicate some TLRs in tumor development based on their ability to facilitate tumor growth; however, to our knowledge, involvement of neither TLR7 nor TLR78 has y...

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Bibliographische Detailangaben
Hauptverfasser: Cherfils-Vicini, Julien, Platonova, Sophia, Gillard, Mélanie, Laurans, Ludivine, Validire, Pierre, Caliandro, Rafaele, Magdeleinat, Pierre, Mami-Chouaib, Fathia, Dieu-Nosjean, Marie-Caroline, Fridman, Wolf-Herman, Damotte, Diane, Sautès-Fridman, Catherine, Cremer, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846035/
https://ncbi.nlm.nih.gov/pubmed/20237413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36551
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