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Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Appropriate localization and migration of T cells is a prerequisite for antitumor immune surveillance. Studies using fixed tumor samples from human patients have shown that T cells accumulate more efficiently in the stroma than in tumor islets, but the mechanisms by which this occurs are unknown. By...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287213/ https://ncbi.nlm.nih.gov/pubmed/22293174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45817 |
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