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Within tumors, interactions between T cells and tumor cells are impeded by the extracellular matrix

In principle, T cells can recognize and kill cancer cells. However, tumors have the ability to escape T cell attack. By imaging the dynamic behavior of T cells in human lung tumor explants, we have recently established the importance of the extracellular matrix in limiting access of T cells to tumor...

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Bibliographic Details
Main Authors: Salmon, Hélène, Donnadieu, Emmanuel
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489771/
https://ncbi.nlm.nih.gov/pubmed/23162783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20239
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