Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

Immunometabolism revealed the crucial role of cellular metabolism in controlling immune cell phenotype and functions. Macrophages, key immune cells that support progression of numerous inflammatory diseases, have been well described as undergoing vast metabolic rewiring upon activation. The immunome...

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Bibliographic Details
Published in:Metabolites
Main Authors: Harber, Karl J., de Goede, Kyra E., Verberk, Sanne G. S., Meinster, Elisa, de Vries, Helga E., van Weeghel, Michel, de Winther, Menno P. J., Van den Bossche, Jan
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569821/
https://ncbi.nlm.nih.gov/pubmed/32942769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10090372
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