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Cucurbitacin E and I target the JAK/STAT pathway and induce apoptosis in Sézary cells
Cutaneous T-cell lymphomas and leukemias (CTCLs) are a heterogeneous group of extranodal non-Hodgkin's lymphomas. These are characterized by an accumulation of malignant CD4(+) T-lymphocytes in the skin, lymph nodes, and peripheral blood. Novel treatment options are needed for patients who prog...
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| Publicat a: | Biochem Biophys Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7569298/ https://ncbi.nlm.nih.gov/pubmed/33102814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100832 |
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