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Cryopreservation impairs 3-D migration and cytotoxicity of natural killer cells

Natural killer (NK) cells are important effector cells in the immune response to cancer. Clinical trials on adoptively transferred NK cells in patients with solid tumors, however, have thus far been unsuccessful. As NK cells need to pass stringent safety evaluation tests before clinical use, the cel...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mark, Christoph, Czerwinski, Tina, Roessner, Susanne, Mainka, Astrid, Hörsch, Franziska, Heublein, Lucas, Winterl, Alexander, Sanokowski, Sebastian, Richter, Sebastian, Bauer, Nina, Angelini, Thomas E., Schuler, Gerold, Fabry, Ben, Voskens, Caroline J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568558/
https://ncbi.nlm.nih.gov/pubmed/33067467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19094-0
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