A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity

KEY POINTS: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to eliminate cancer cells. We analysed the Ca(2+) dependence of CTL and NK cell cytotoxicity and found that in particular CTLs have a very low optimum of [Ca(2+)](i) (between 122 and 334 nm) and [Ca(2+)](o) (betwee...

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Xehetasun bibliografikoak
Argitaratua izan da:J Physiol
Egile Nagusiak: Zhou, Xiao, Friedmann, Kim S., Lyrmann, Hélène, Zhou, Yan, Schoppmeyer, Rouven, Knörck, Arne, Mang, Sebastian, Hoxha, Cora, Angenendt, Adrian, Backes, Christian S., Mangerich, Carmen, Zhao, Renping, Cappello, Sabrina, Schwär, Gertrud, Hässig, Carmen, Neef, Marc, Bufe, Bernd, Zufall, Frank, Kruse, Karsten, Niemeyer, Barbara A., Lis, Annette, Qu, Bin, Kummerow, Carsten, Schwarz, Eva C., Hoth, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Special section: Intracellular calcium signalling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046087/
https://ncbi.nlm.nih.gov/pubmed/29368348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274964
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