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Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8(+) T cells of elderly mice
Ca(2+) is a crucial second messenger for proper T cell function. Considering the relevance of Ca(2+) signals for T cell functionality it is surprising that no mechanistic insights into T cell Ca(2+) signals from elderly individuals are reported. The main Ca(2+) entry mechanism in T cells are STIM-ac...
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| Udgivet i: | Aging (Albany NY) |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066920/ https://ncbi.nlm.nih.gov/pubmed/32062611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102809 |
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