A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity

KEY POINTS: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to eliminate cancer cells. We analysed the Ca(2+) dependence of CTL and NK cell cytotoxicity and found that in particular CTLs have a very low optimum of [Ca(2+)](i) (between 122 and 334 nm) and [Ca(2+)](o) (betwee...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Physiol
Hauptverfasser: Zhou, Xiao, Friedmann, Kim S., Lyrmann, Hélène, Zhou, Yan, Schoppmeyer, Rouven, Knörck, Arne, Mang, Sebastian, Hoxha, Cora, Angenendt, Adrian, Backes, Christian S., Mangerich, Carmen, Zhao, Renping, Cappello, Sabrina, Schwär, Gertrud, Hässig, Carmen, Neef, Marc, Bufe, Bernd, Zufall, Frank, Kruse, Karsten, Niemeyer, Barbara A., Lis, Annette, Qu, Bin, Kummerow, Carsten, Schwarz, Eva C., Hoth, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Special section: Intracellular calcium signalling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046087/
https://ncbi.nlm.nih.gov/pubmed/29368348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274964
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge