A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity

KEY POINTS: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to eliminate cancer cells. We analysed the Ca(2+) dependence of CTL and NK cell cytotoxicity and found that in particular CTLs have a very low optimum of [Ca(2+)](i) (between 122 and 334 nm) and [Ca(2+)](o) (betwee...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Physiol
Hlavní autoři: Zhou, Xiao, Friedmann, Kim S., Lyrmann, Hélène, Zhou, Yan, Schoppmeyer, Rouven, Knörck, Arne, Mang, Sebastian, Hoxha, Cora, Angenendt, Adrian, Backes, Christian S., Mangerich, Carmen, Zhao, Renping, Cappello, Sabrina, Schwär, Gertrud, Hässig, Carmen, Neef, Marc, Bufe, Bernd, Zufall, Frank, Kruse, Karsten, Niemeyer, Barbara A., Lis, Annette, Qu, Bin, Kummerow, Carsten, Schwarz, Eva C., Hoth, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Special section: Intracellular calcium signalling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046087/
https://ncbi.nlm.nih.gov/pubmed/29368348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274964
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky