A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity

KEY POINTS: Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells are required to eliminate cancer cells. We analysed the Ca(2+) dependence of CTL and NK cell cytotoxicity and found that in particular CTLs have a very low optimum of [Ca(2+)](i) (between 122 and 334 nm) and [Ca(2+)](o) (betwee...

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Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Zhou, Xiao, Friedmann, Kim S., Lyrmann, Hélène, Zhou, Yan, Schoppmeyer, Rouven, Knörck, Arne, Mang, Sebastian, Hoxha, Cora, Angenendt, Adrian, Backes, Christian S., Mangerich, Carmen, Zhao, Renping, Cappello, Sabrina, Schwär, Gertrud, Hässig, Carmen, Neef, Marc, Bufe, Bernd, Zufall, Frank, Kruse, Karsten, Niemeyer, Barbara A., Lis, Annette, Qu, Bin, Kummerow, Carsten, Schwarz, Eva C., Hoth, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Special section: Intracellular calcium signalling
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046087/
https://ncbi.nlm.nih.gov/pubmed/29368348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274964
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