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Alternative proton-binding site and long-distance coupling in Escherichia coli sodium–proton antiporter NhaA

Escherichia coli NhaA is a prototypical sodium–proton antiporter responsible for maintaining cellular ion and volume homeostasis by exchanging two protons for one sodium ion; despite two decades of research, the transport mechanism of NhaA remains poorly understood. Recent crystal structure and comp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Henderson, Jack A., Huang, Yandong, Beckstein, Oliver, Shen, Jana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568328/
https://ncbi.nlm.nih.gov/pubmed/32973095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005467117
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