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Mechanism of pH-dependent activation of the sodium-proton antiporter NhaA

Escherichia coli NhaA is a prototype sodium-proton antiporter, which has been extensively characterized by X-ray crystallography, biochemical and biophysical experiments. However, the identities of proton carriers and details of pH-regulated mechanism remain controversial. Here we report constant pH...

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Publicado en:Nat Commun
Main Authors: Huang, Yandong, Chen, Wei, Dotson, David L., Beckstein, Oliver, Shen, Jana
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059715/
https://ncbi.nlm.nih.gov/pubmed/27708266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12940
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