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Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis
In sum, we show that MSCs manipulate the intrinsic activation pathway of CD8+T cells to affect their functional outcome, which results in differential immune activation or suppression.
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| Publié dans: | Stem Cells |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568282/ https://ncbi.nlm.nih.gov/pubmed/24911892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1755 |
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