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Distinct Functions of Autoreactive Memory and Effector CD4(+) T Cells in Experimental Autoimmune Encephalomyelitis
The persistence of human autoimmune diseases is thought to be mediated predominantly by memory T cells. We investigated the phenotype and migration of memory versus effector T cells in vivo in experimental autoimmune encephalomyelitis (EAE). We found that memory CD4(+) T cells up-regulated the activ...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Investigative Pathology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475778/ https://ncbi.nlm.nih.gov/pubmed/18583313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080142 |
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