Distinct Functions of Autoreactive Memory and Effector CD4(+) T Cells in Experimental Autoimmune Encephalomyelitis

The persistence of human autoimmune diseases is thought to be mediated predominantly by memory T cells. We investigated the phenotype and migration of memory versus effector T cells in vivo in experimental autoimmune encephalomyelitis (EAE). We found that memory CD4(+) T cells up-regulated the activ...

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Hlavní autoři: Elyaman, Wassim, Kivisäkk, Pia, Reddy, Jay, Chitnis, Tanuja, Raddassi, Khadir, Imitola, Jaime, Bradshaw, Elizabeth, Kuchroo, Vijay K., Yagita, Hideo, Sayegh, Mohamed H., Khoury, Samia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2008
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475778/
https://ncbi.nlm.nih.gov/pubmed/18583313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080142
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