Elevated Neuronal Expression of CD200 Protects Wld(s) Mice from Inflammation-Mediated Neurodegeneration

Axonal damage secondary to inflammation is likely the substrate of chronic disability in multiple sclerosis and is found in the animal model of experimental autoimmune encephalomyelitis (EAE). Wld(s) mice have a triplication of the fusion gene Ube4b/Nmnat and a phenotype of axon protection. Wld(s) m...

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Autores principales: Chitnis, Tanuja, Imitola, Jaime, Wang, Yue, Elyaman, Wassim, Chawla, Prianka, Sharuk, Maia, Raddassi, Khadir, Bronson, Roderick T., Khoury, Samia J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2007
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854964/
https://ncbi.nlm.nih.gov/pubmed/17456775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060677
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