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Subunit-selective iGluR antagonists can potentiate heteromeric receptor responses by blocking desensitization
Ionotropic glutamate receptors (iGluRs) are key molecules for synaptic signaling in the central nervous system, which makes them promising drug targets. Intensive efforts are being devoted to the development of subunit-selective ligands, which should enable more precise pharmacologic interventions w...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568280/ https://ncbi.nlm.nih.gov/pubmed/32999066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007471117 |
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