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Subunit-selective iGluR antagonists can potentiate heteromeric receptor responses by blocking desensitization
Ionotropic glutamate receptors (iGluRs) are key molecules for synaptic signaling in the central nervous system, which makes them promising drug targets. Intensive efforts are being devoted to the development of subunit-selective ligands, which should enable more precise pharmacologic interventions w...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568280/ https://ncbi.nlm.nih.gov/pubmed/32999066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007471117 |
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