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Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71
Enterovirus 71 (EV71)-neutralizing antibodies correlate with protection and have potential as therapeutic agents. We isolate and characterize a panel of plasmablast-derived monoclonal antibodies from an infected child whose antibody response focuses on the plateau epitope near the icosahedral 3-fold...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567869/ https://ncbi.nlm.nih.gov/pubmed/33067459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19013-3 |
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