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Targeted Delivery of an siRNA/PNA Hybrid Nanocomplex Reverses Carbon Tetrachloride‐Induced Liver Fibrosis

Liver fibrosis is a wound healing process with excessive accumulation of extracellular matrix in the liver. We recently discovered a PCBP2 siRNA that reverses fibrogenesis in activated hepatic stellate cells (HSCs), which are the key players in liver fibrogenesis. However, targeted delivery of siRNA...

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Detalhes bibliográficos
Publicado no:Adv Ther (Weinh)
Main Authors: Jain, Akshay, Barve, Ashutosh, Zhao, Zhen, Fetse, John Peter, Liu, Hao, Li, Yuanke, Cheng, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567403/
https://ncbi.nlm.nih.gov/pubmed/33072857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.201900046
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