Aberrant Notch1-dependent effects on glomerular parietal epithelial cells promotes collapsing focal segmental glomerulosclerosis with progressive podocyte loss

Collapsing focal segmental glomerulosclerosis (cFSGS) is a progressive kidney disease characterized by glomerular collapse with epithelial hyperplasia. Here we used a transgenic mouse model of cFSGS with immunotoxin-induced podocyte-specific injury to determine the role for Notch signaling in its pa...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Ueno, Toshiharu, Kobayashi, Namiko, Nakayama, Makiko, Takashima, Yasutoshi, Ohse, Takamoto, Pastan, Ira, Pippin, Jeffrey W., Shankland, Stuart J., Uesugi, Noriko, Matsusaka, Taiji, Nagata, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567340/
https://ncbi.nlm.nih.gov/pubmed/23447065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.48
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