The Histone Methyltransferase SETDB1 Modulates Survival of Spermatogonial Stem/Progenitor Cells Through NADPH Oxidase

SETDB1, a histone H3 lysine 9 (H3K9) methyltransferase, is crucial in meiosis and embryo development. This study aimed to investigate whether SETDB1 was associated with spermatogonial stem cells (SSC) homeostasis. We found that knockdown of Setdb1 impaired cell proliferation, led to an increase in r...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Genet
Главные авторы: Li, Xueliang, Chen, Xiaoxu, Liu, Yingdong, Zhang, Pengfei, Zheng, Yi, Zeng, Wenxian
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Genetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567028/
https://ncbi.nlm.nih.gov/pubmed/33133132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00997
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы