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Clinical impact of combined epigenetic and molecular analysis of pediatric low-grade gliomas

BACKGROUND: Both genetic and methylation analysis have been shown to provide insight into the diagnosis and prognosis of many brain tumors. However, the implication of methylation profiling and its interaction with genetic alterations in pediatric low-grade gliomas (PLGGs) are unclear. METHODS: We p...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Fukuoka, Kohei, Mamatjan, Yasin, Tatevossian, Ruth, Zapotocky, Michal, Ryall, Scott, Stucklin, Ana Guerreiro, Bennett, Julie, Nobre, Liana Figueiredo, Arnoldo, Anthony, Luu, Betty, Wen, Ji, Zhu, Kaicen, Leon, Alberto, Torti, Dax, Pugh, Trevor J, Hazrati, Lili-Naz, Laperriere, Normand, Drake, James, Rutka, James T, Dirks, Peter, Kulkarni, Abhaya V, Taylor, Michael D, Bartels, Ute, Huang, Annie, Zadeh, Gelareh, Aldape, Kenneth, Ramaswamy, Vijay, Bouffet, Eric, Snuderl, Matija, Ellison, David, Hawkins, Cynthia, Tabori, Uri
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566385/
https://ncbi.nlm.nih.gov/pubmed/32242226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa077
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