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Mutant huntingtin does not cross the mitochondrial outer membrane
Mutant huntingtin (mHTT) is associated with mitochondria, but the exact mitochondrial location of mHTT has not been definitively established. Recently, it was reported that mHTT is present in the intermembrane space and inhibits mitochondrial protein import by interacting with TIM23, a major compone...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566381/ https://ncbi.nlm.nih.gov/pubmed/32821928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa185 |
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