Therapeutic effect of TRC105 and decitabine combination in AML xenografts

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy, often characterized by poor prognosis following standard induction therapy. The hypomethylating agent decitabine (DAC) is an alternative treatment for elderly and relapsed/refractory AML patients, yet responses following DAC monot...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Baik, June, Felices, Martin, Yingst, Ashley, Theuer, Charles P., Verneris, Michael R., Miller, Jeffrey S., Perlingeiro, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566100/
https://ncbi.nlm.nih.gov/pubmed/33088975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05242
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