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Effects of the combination of TRC105 and bevacizumab on endothelial cell biology

Endoglin, or CD105, is a cell membrane glycoprotein that is overexpressed on proliferating endothelial cells (EC), including those found in malignancies and choroidal neovascularization. Endoglin mediates the transition from quiescent endothelium, characterized by the relatively dominant state of Sm...

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Detalhes bibliográficos
Main Authors: Liu, Yingmiao, Tian, Hongyu, Blobe, Gerard C., Theuer, Charles P., Hurwitz, Herbert I., Nixon, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169868/
https://ncbi.nlm.nih.gov/pubmed/24994097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0129-y
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