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Effects of the combination of TRC105 and bevacizumab on endothelial cell biology
Endoglin, or CD105, is a cell membrane glycoprotein that is overexpressed on proliferating endothelial cells (EC), including those found in malignancies and choroidal neovascularization. Endoglin mediates the transition from quiescent endothelium, characterized by the relatively dominant state of Sm...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer US
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169868/ https://ncbi.nlm.nih.gov/pubmed/24994097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0129-y |
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