Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models

Endoglin (CD105), a receptor of the transforming growth factor-β superfamily, has been reported to identify functional long-term repopulating hematopoietic stem cells, and has been detected in certain subtypes of acute leukemias. Whether this receptor plays a functional role in leukemogenesis remain...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Dourado, Keina M. C., Baik, June, Oliveira, Vanessa K. P., Beltrame, Miriam, Yamamoto, Ami, Theuer, Charles P., Figueiredo, Camila A. V., Verneris, Michael R., Perlingeiro, Rita C. R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418640/
https://ncbi.nlm.nih.gov/pubmed/28351936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-01-763581
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