A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2 diabetes. Animal models adequately mimicking this condition are scarce. We herein investigate whether Ldlr−/−. Leiden mice on different high-fat d...

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Publicado no:Cells
Main Authors: van den Hoek, Anita M., Verschuren, Lars, Worms, Nicole, van Nieuwkoop, Anita, de Ruiter, Christa, Attema, Joline, Menke, Aswin L., Caspers, Martien P. M., Radhakrishnan, Sridhar, Salic, Kanita, Kleemann, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565967/
https://ncbi.nlm.nih.gov/pubmed/32883049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092014
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