A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology

Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2 diabetes. Animal models adequately mimicking this condition are scarce. We herein investigate whether Ldlr−/−. Leiden mice on different high-fat d...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: van den Hoek, Anita M., Verschuren, Lars, Worms, Nicole, van Nieuwkoop, Anita, de Ruiter, Christa, Attema, Joline, Menke, Aswin L., Caspers, Martien P. M., Radhakrishnan, Sridhar, Salic, Kanita, Kleemann, Robert
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565967/
https://ncbi.nlm.nih.gov/pubmed/32883049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092014
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