Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

Alcaligenes spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that Alcaligenes-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without excessive inflammation. Lipid A is one of the componen...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Wang, Yunru, Hosomi, Koji, Shimoyama, Atsushi, Yoshii, Ken, Yamaura, Haruki, Nagatake, Takahiro, Nishino, Tomomi, Kiyono, Hiroshi, Fukase, Koichi, Kunisawa, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565795/
https://ncbi.nlm.nih.gov/pubmed/32698404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030395
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