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Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

Alcaligenes spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that Alcaligenes-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without excessive inflammation. Lipid A is one of the componen...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Wang, Yunru, Hosomi, Koji, Shimoyama, Atsushi, Yoshii, Ken, Yamaura, Haruki, Nagatake, Takahiro, Nishino, Tomomi, Kiyono, Hiroshi, Fukase, Koichi, Kunisawa, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565795/
https://ncbi.nlm.nih.gov/pubmed/32698404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030395
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