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Selective Interferon Responses of Intestinal Epithelial Cells Minimize Tumor Necrosis Factor Alpha Cytotoxicity

Interferon (IFN) family cytokines stimulate genes (interferon-stimulated genes [ISGs]) that are integral to antiviral host defense. Type I IFNs act systemically, whereas type III IFNs act preferentially at epithelial barriers. Among barrier cells, intestinal epithelial cells (IECs) are particularly...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Van Winkle, Jacob A., Constant, David A., Li, Lena, Nice, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565621/
https://ncbi.nlm.nih.gov/pubmed/32847859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00603-20
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