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Unpaired Guanosines in the 5′ Untranslated Region of HIV-1 RNA Act Synergistically To Mediate Genome Packaging

The viral protein Gag selects full-length HIV-1 RNA from a large pool of mRNAs as virion genome during virus assembly. Currently, the precise mechanism that mediates the genome selection is not understood. Previous studies have identified several sites in the 5′ untranslated region (5′ UTR) of HIV-1...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nikolaitchik, Olga A., Somoulay, Xayathed, Rawson, Jonathan M. O., Yoo, Jennifer A., Pathak, Vinay K., Hu, Wei-Shau
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565613/
https://ncbi.nlm.nih.gov/pubmed/32796062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00439-20
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