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Unpaired Guanosines in the 5′ Untranslated Region of HIV-1 RNA Act Synergistically To Mediate Genome Packaging

The viral protein Gag selects full-length HIV-1 RNA from a large pool of mRNAs as virion genome during virus assembly. Currently, the precise mechanism that mediates the genome selection is not understood. Previous studies have identified several sites in the 5′ untranslated region (5′ UTR) of HIV-1...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Nikolaitchik, Olga A., Somoulay, Xayathed, Rawson, Jonathan M. O., Yoo, Jennifer A., Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565613/
https://ncbi.nlm.nih.gov/pubmed/32796062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00439-20
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