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Unpaired Guanosines in the 5′ Untranslated Region of HIV-1 RNA Act Synergistically To Mediate Genome Packaging

The viral protein Gag selects full-length HIV-1 RNA from a large pool of mRNAs as virion genome during virus assembly. Currently, the precise mechanism that mediates the genome selection is not understood. Previous studies have identified several sites in the 5′ untranslated region (5′ UTR) of HIV-1...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Nikolaitchik, Olga A., Somoulay, Xayathed, Rawson, Jonathan M. O., Yoo, Jennifer A., Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565613/
https://ncbi.nlm.nih.gov/pubmed/32796062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00439-20
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