Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen

T cells recognizing epitopes on the surface of mycobacteria-infected macrophages can impart protection, but with associated risk for reactivation to lung pathology. We aimed to identify antibodies specific to such epitopes, which carry potentials for development toward novel therapeutic constructs....

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Veröffentlicht in:Front Immunol
Hauptverfasser: Ortega, Paola A., Silva-Miranda, Mayra, Torres-Larios, Alfredo, Campos-Chávez, Eduardo, Franken, Kees C. L. C. M., Ottenhoff, Tom H. M., Ivanyi, Juraj, Espitia, Clara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564862/
https://ncbi.nlm.nih.gov/pubmed/33117380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.577815
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