Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen

T cells recognizing epitopes on the surface of mycobacteria-infected macrophages can impart protection, but with associated risk for reactivation to lung pathology. We aimed to identify antibodies specific to such epitopes, which carry potentials for development toward novel therapeutic constructs....

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Ortega, Paola A., Silva-Miranda, Mayra, Torres-Larios, Alfredo, Campos-Chávez, Eduardo, Franken, Kees C. L. C. M., Ottenhoff, Tom H. M., Ivanyi, Juraj, Espitia, Clara
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564862/
https://ncbi.nlm.nih.gov/pubmed/33117380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.577815
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