Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen

T cells recognizing epitopes on the surface of mycobacteria-infected macrophages can impart protection, but with associated risk for reactivation to lung pathology. We aimed to identify antibodies specific to such epitopes, which carry potentials for development toward novel therapeutic constructs....

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Ortega, Paola A., Silva-Miranda, Mayra, Torres-Larios, Alfredo, Campos-Chávez, Eduardo, Franken, Kees C. L. C. M., Ottenhoff, Tom H. M., Ivanyi, Juraj, Espitia, Clara
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564862/
https://ncbi.nlm.nih.gov/pubmed/33117380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.577815
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